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Airdrie Metabolic Health

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Insulin Resistance: Clinical Basics

A practical overview of insulin resistance, why it develops, and what to measure first.

Tags: diabetes • insulin resistance • fasting

Key concept

Insulin resistance means tissues need more insulin to manage the same glucose load. Over time, this can raise glucose, triglycerides, blood pressure, and waist circumference.

Common clues

  • Rising fasting glucose or A1C
  • Elevated triglycerides with low HDL
  • Central adiposity
  • Post-meal fatigue and hunger cycling

First-line lifestyle focus

  1. Increase protein and reduce ultra-processed carbohydrate intake.
  2. Add daily movement and structured resistance work.
  3. Improve sleep regularity and stress regulation.
  4. Consider structured fasting where appropriate.

Why early action matters

Earlier intervention improves the chance of reversing metabolic trends before medication intensity escalates.

References

  1. Insulin Resistance and Prediabetes (The Lancet (2012)) Link
  2. Type 2 Diabetes Prevention and Lifestyle Intervention (Diabetes Care) Link
  3. Pathogenesis of Type 2 Diabetes (Endotext) Link

Next step

Turn reading into action

Book an in-person consultation to tailor these strategies safely to your health profile.